作者: J. Salinas , M. Virseda , M.P. Fuente , F. Mellado , A.C. Uson
DOI: 10.1159/000282423
关键词: Calcium 、 Cholinergic 、 Endocrinology 、 Calcium in biology 、 Medicine 、 Verapamil 、 Atropine 、 Fissipedia 、 Carnivora 、 Internal medicine 、 EGTA
摘要: This experimental study was designed and carried out in order to investigate the participation of collagen muscular tissues on viscoelastic properties bladder wall. Sixty-five adult male mongrel dogs were utilized. These animals divided into 5 groups: control group (n = 10); 10) receiving 2.5 mg/kg atropine (cholinergic antagonist); 0.7mg/kg verapamil (calcium extracellular inflow blocker); 0.1 mg/kg/min nitroprusside (intracellular calcium blocker), 25) EGTA (a calcium-chelating agent) at increasing doses from 90 450 mg/kg. Based a mathematical model, we have demonstrated that: (1) component is responsible for elastic properties; (2) muscle (3) an active element which affected by total depletion, (4) such are not dependent cholinergic stimulation.