The multi-potentiality of skin-derived stem cells in pigs
作者： Ming-Tao Zhao , R.S. Prather
DOI: 10.1016/J.THERIOGENOLOGY.2010.06.010
关键词: Cell biology 、 Cancer stem cell 、 Molecular biology 、 Induced stem cells 、 Cell potency 、 Neural stem cell 、 Stem cell marker 、 Stem cell 、 Biology 、 Adult stem cell 、 Neurosphere 、 Food Animals 、 Animal Science and Zoology 、 Equine 、 Small Animals
摘要: Multipotent skin-derived stem cells represent neural-crest derived precursors which have neural and mesodermal potency can generate neurons, glias, smooth muscle cells, adipocytes. Transcriptional profiling studies show that both intrinsic programs extrinsic signaling pathways mediate their potency. In addition, recent progress implies may a broader developmental than previously expected, of is potential to germline in vitro. this review, we discuss the transcriptional multipotency crest-derived characteristics argue for germ-line competency view nuclear cellular reprogramming.
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