Human immune responses during schistosomiasis mansoni

作者: Giovanni Gazzinelli , Daniel G. Colley

DOI: 10.1590/S0037-86821992000200006

关键词: Immune systemIn patientChronic exposureBiologySchistosomiasisImmune mechanismsImmunology

摘要: Studies of immune responses as they occur in patients with schistosomiasis appear to progress relative corrent technological advances, and advance despite the understandable inability pursue vivo manipulations this host/parasite system. Emphasis is most often placed on making immunological comparisons between such patient groups reinfected/non-reinfected, intestinals/hepatosplenic, high/low intensities infection, infected/uninfected within endemic areas, those born mothers. Based these types comparisons, reasonable conjectures can be made regarding occurrences during chronic exposure condition. Some consideration now being given mechanisms some observations made, while must then carried back experimental models for further manipulation-based analysis, new developments continue assist field/bench ability ask questions that might our understanding a point where knowledge applied shaping developmental approaches vaccine development goal alleviating morbidity.

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