Prévention des seconds cancers primaires par supplémentation vitaminique chez les patients traités pour un cancer ORL
作者： I Bairati , F Brochet , J Roy , M Gélinas , A Nabid
DOI: 10.1016/0924-4212(96)81345-4
关键词: Vitamine e 、 Second primary cancer 、 Gynecology 、 Medicine
摘要: Resume La survie des patients traites pour un cancer ORL de stade precoce est souvent compromise par la survenue d'un deuxieme primaire. Des etudes experimentales chez l'animal et donnees epidemiologiques suggerent que les vitamines antioxydantes, en particulier le β-carotene l'alpha-tocopherol, pourraient prevenir ces seconds cancers. Un essai clinique randomise double insu cours au Canada evaluer si une supplementation combinant (30 mg/j) l'alpha-tocopherol (400 UI/j) diminue l'incidence cancers radiotherapie premier ORL.
sci-hub.se 参考文章(36)
Hans F. STICH, A. Paul HORNBY, Bruce P. DUNN, A pilot beta-carotene intervention trial with Inuits using smokeless tobacco. International Journal of Cancer. ,vol. 36, pp. 321- 327 ,(1985) , 10.1002/IJC.1985.36.3.321
Susan Taylor Mayne, Tongzhang Zheng, Dwight T. Janerich, W. Jarrard Goodwin, Barbara G. Fallon, Dennis L. Cooper, Craig D. Friedman, A population-based trial of β-carotene chemoprevention of head and neck cancer Advances in Experimental Medicine and Biology. ,vol. 320, pp. 119- 127 ,(1992) , 10.1007/978-1-4615-3468-6_16
William J. Blot, Vicki Spate, Wei Zheng, George W. Comstock, Earl L. Diamond, Edward P. Norkus, John S. Morris, Serum micronutrients and the subsequent risk of oral and pharyngeal cancer. Cancer Research. ,vol. 53, pp. 795- 798 ,(1993)
Joel Schwartz, Gerald Shklar, Regression of experimental oral carcinomas by local injection of β‐carotene and canthaxanthin Nutrition and Cancer. ,vol. 11, pp. 35- 40 ,(1988) , 10.1080/01635588809513967
Waun KI Hong, Scott M. Lippman, Loretta M. Itri, Daniel D. Karp, Jin S. Lee, Robert M. Byers, Stimson P. Schantz, Alan M. Kramer, Reuben Lotan, Lester J. Peters, Isaiah W. Dimery, Barry W. Brown, Helmuth Goepfert, Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. The New England Journal of Medicine. ,vol. 323, pp. 795- 801 ,(1990) , 10.1056/NEJM199009203231205
N. de Vries, G. B. Snow, Relationships of vitamins A and E and beta-carotene serum levels to head and neck cancer patients with and without second primary tumors. European Archives of Oto-rhino-laryngology. ,vol. 247, pp. 368- 370 ,(1990) , 10.1007/BF00179009
S. E. Benner, R. J. Winn, S. M. Lippman, J. Poland, K. S. Hansen, M. A. Luna, W. K. Hong, Regression of oral leukoplakia with α-tocopherol : a community clinical oncology program chemoprevention study Journal of the National Cancer Institute. ,vol. 85, pp. 44- 47 ,(1993) , 10.1093/JNCI/85.1.44
P. Cerutti, Prooxidant states and tumor promotion Science. ,vol. 227, pp. 375- 381 ,(1985) , 10.1126/SCIENCE.2981433
Onatolu Odukoya, Farouk Hawach, Gerald Shklar, Retardation of experimental oral cancer by topical vitamin E Nutrition and Cancer. ,vol. 6, pp. 98- 104 ,(1985) , 10.1080/01635588509513813
Jay S. Cooper, Thomas F. Pajak, Philip Rubin, Leslie Tupchong, Luther W. Brady, Steven A. Leibel, George E. Laramore, Victor A. Marcial, Lawrence W. Davis, James D. Cox, Second malignancies in patients who have head and neck cancer: incidence, effect on survival and implications based on the RTOG experience. International Journal of Radiation Oncology Biology Physics. ,vol. 17, pp. 449- 456 ,(1989) , 10.1016/0360-3016(89)90094-1