Pathology of Shy-Drager Syndrome

作者: Joo Ho Sung , Angeline R. Mastri , Edward Segal

DOI: 10.1097/00005072-197907000-00001

关键词: Autonomic nervous systemOlivopontocerebellar atrophyOnuf's nucleusPathologyStriatonigral DegenerationAnatomyCorticospinal tractAnterior Horn CellTissue DegenerationBiologyCentral nervous system

摘要: In four patients with the Shy-Drager syndrome, detailed pathological findings in central nervous system are described. All had striatonigral degeneration, olivopontocerebellar atrophy, pyramidal tract degeneration and ventral horn cell loss. Along multisystem there was widespread loss of thoracolumbar autonomic neurons, which demonstrated by comparative counts intermediolateral horns two patients. all patients, nuclei sacral cord, particularly Onuf's nuclei, were severely affected diffuse seems to account for disordered bladder, rectal sexual functions syndrome.

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