Modified Radical Hysterectomy in the Treatment of Early Squamous Cervical Cancer

作者: Javier F. Magrina , Martha A. Goodrich , Thomas K. Lidner , Amy L. Weaver , Jeffrey L. Cornella

DOI: 10.1006/GYNO.1998.5245

关键词: Lymph nodeHysterectomyUrologyEpidermoid carcinomaMedicineCarcinomaSurvival analysisUnivariate analysisCervical cancerSurvival rateSurgery

摘要: Abstract Objective. The aim of this study was to evaluate the results modified radical hysterectomy in treatment early cervical cancer. Material and Methods. A retrospective chart review 56 patients with stage I (IA 35, IB 21) squamous carcinoma treated followed for a minimum 5 years (mean, 12 years; range, 5.1–29) conducted. All pathology slides were reviewed tumor size, grade, depth invasion, lymph–vascular permeation. Results. mean invasion 0.5 cm (range, 0.1–2.5 cm), size 1.1 0.1–7 cm). Only 3 (5.4%) had positive nodes. None tumors 2 or less nodes, whereas 33.3% more than recurrence developed (5-year rate 3.6%). There 10 deaths during entire follow-up period, but only related disease-specific overall 5-year survival rates 96.4 94.6%, respectively. 100% among 47 75% 9 larger cm. Univariate analysis identified stage, lymph node status, as statistically significant prognostic factors survival. Tumor permeation, (1–3 mm vs >3 mm) not Conclusions. Modified appears be effective surgical therapy size.

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