Candida invasion and influences in smoking patients with multiple oral leucoplakias--a retrospective study.

作者: Chang-Ta Chiu , Chien-Feng Li , Jau-Rong Li , Johnny Wang , Ching-Ya Chuang

DOI: 10.1111/J.1439-0507.2010.01927.X

关键词: PathologyRisk factorGastroenterologyIncidence (epidemiology)Retrospective cohort studyInternal medicineEpithelial dysplasiaOral leucoplakiaMedicineEtiologyComplete resection

摘要: Summary Treating patients with multiple oral leucoplakias (MOLs) who smoke is more difficult and complicated than treating those single leucoplakia (SOL). Removing the aetiological factors causing MOL can effectively prevent its recurrence. The aim was to study infection by influences of Candida in smoking MOLs. A retrospective conducted on 136 had clinicopathological OLs. Among these patients, 73 lesions 31 were MOLs, while 105 SOLs. All treated complete resection. specimens tested for epithelial dysplasia, stained periodic acid–Schiff reagent. rate concurrence candidal higher that incidence associated MOLs recurrent non-recurrent lesions. disease-free time shorter infection. Moreover, likely have an increasing ratio combine dysplasia. important risk factor Microscopic fungal examinations should permit a detailed diagnosis such long-term predictive assessments.

参考文章(37)
Bouquot Je, Oral leukoplakia and erythroplakia: a review and update. Practical periodontics and aesthetic dentistry : PPAD. ,vol. 6, pp. 9- ,(1994)
Jolán Bánóczy, Zeno Gintner, Csaba Dombi, Tobacco use and oral leukoplakia Journal of Dental Education. ,vol. 65, pp. 322- 327 ,(2001) , 10.1002/J.0022-0337.2001.65.4.TB03402.X
A. Ali, S. Natah, Y. Konttinen, Differential expression of Toll-like receptors in chronic hyperplastic candidosis. Oral Microbiology and Immunology. ,vol. 23, pp. 299- 307 ,(2008) , 10.1111/J.1399-302X.2007.00428.X
Judith Berman, Peter E. Sudbery, Candida albicans : A molecular revolution built on lessons from budding yeast Nature Reviews Genetics. ,vol. 3, pp. 918- 930 ,(2002) , 10.1038/NRG948
Sol Silverman Jr, Meir Gorsky, Francina Lozada, Dds, Ms, Oral leukoplakia and malignant transformation. A follow-up study of 257 patients Cancer. ,vol. 53, pp. 563- 568 ,(1984) , 10.1002/1097-0142(19840201)53:3<563::AID-CNCR2820530332>3.0.CO;2-F
A. M. Willis, W. A. Coulter, C. R. Fulton, J. R. Hayes, P. M. Bell, P. -J. Lamey, Oral candidal carriage and infection in insulin-treated diabetic patients Diabetic Medicine. ,vol. 16, pp. 675- 679 ,(1999) , 10.1046/J.1464-5491.1999.00134.X
A. Wright, M. Shear, Epithelial dysplasia immediately adjacent to oral squamous cell carcinomas. Journal of Oral Pathology & Medicine. ,vol. 14, pp. 559- 564 ,(1985) , 10.1111/J.1600-0714.1985.TB00529.X