Chronic disease comorbidity in patients with oral leukoplakia

摘要: Oral leukoplakia represents the most common oral potentially malignant disorder. While a number of risk factors have been identified, its aetiology remains incompletely understood, and prediction disease progression, stability or regression, significant challenge. excision is often recommended treatment to reduce malignancy, this not always possible ultimately numerous patient characteristics impact on decision initiate recommend surveillance. At present, coexistence chronic diseases in patients largely unexplored, yet has potential significantly diagnosis, decisions, outcomes prognosis. Exploration comorbid conditions may additionally lead greater insight pathogenesis offer more opportunities for screening early detection. The aim review stimulate discussion about role comorbidity leukoplakia.