The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention
作者： Jan Philipp Klein , Thomas Berger , Johanna Schröder , Christina Späth , Björn Meyer
关键词: Health care 、 Patient satisfaction 、 Research design 、 Severity of illness 、 Quality of life (healthcare) 、 Depression (differential diagnoses) 、 Psychiatry 、 Psychological intervention 、 Medicine 、 Randomized controlled trial
摘要: Background: Depressive disorders are among the leading causes of worldwide disability with mild to moderate forms depression being particularly common. Low-intensity treatments such as online psychological may be an effective way treat depressive symptoms and prevent emergence or relapse major depression. Methods/Design: This study is a currently recruiting multicentre parallel-groups pragmatic randomized-controlled single-blind trial. A total 1000 participants from various settings including in- outpatient services will randomized treatment care usual (CAU). We hypothesize that intervention superior CAU in reducing assessed Personal Health Questionnaire (PHQ-9, primary outcome measure) following (12 wks) at follow-up (24 48 wks). Further parameters include quality life, use health resources attitude towards treatments. Discussion: The yield meaningful answers question whether can contribute efficient prevention on population level low barrier entry.
biomedcentral.com
springer.com
paperity.org
uni-bielefeld.de 参考文章(68)
James Bennett-Levy, David Richards, Paul Farrand, Helen Christensen, Kathy Griffiths, David Kavanagh, Britt Klein, Mark A Lau, Judy Proudfoot, Lee Ritterband, Jim White, Chris Williams, None, Oxford guide to low intensity CBT interventions. Oxford University Press. ,(2010) , 10.1093/MED/9780199590117.001.0001
Vikram Patel, Mario Maj, Alan J Flisher, Mary J De Silva, Mirja Koschorke, Martin Prince, WPA Zonal and Member Society Representatives, Raymond Tempier, Michelle Riba, Mauricio Sanchez, Fabrizio Delgado Campodonico, Luis Risco, Linda Gask, Henrik Wahlberg, Miquel Roca, Dusica Lecic‐Tosevski, Armen Soghoyan, Driss Moussaoui, Charles Baddoura, Joseph Adeyemi, Solomon Rataemane, S Ahmed Jalili, E Mohandas, Naotaka Shinfuku, Julian Freidin, Juan Carlos Stagnaro, Ines Josefina Puig, Kenneth Kirkby, Michael Musalek, Nadir Ismayilov, Golam Rabbani, Sharon Harvey, Bernard Sabbe, Nils Noya‐Tapia, Marija Burgic‐Radmanovic, Luiz Alberto Hetem, Fatima Vasconcellos, Juan Maass, Carlos Miranda, Neophytos Papaneophytou, Jiri Raboch, Anders Fink‐Jensen, Ahmed Okasha, Jyrki Korkeila, Julien Daniel Guelfi, Frank Schneider, Sammy Ohene, George Christodoulou, Constantin R Soldatos, Emilio Quinto Barrera See King, Mario Mendoza, Roy Abraham Kallivayalil, Shahrokh S Gudarzi, Mohammed R Lafta, Mariano Bassi, Massimo Clerici, Roger Gibson, Takuya Kojima, Saltanat Nurmagambetova, Soo‐Churl Cho, Tamilla Kadyrova, Nabil Mikati, Sojan Bajraktarov, Teck Hoe Yen, Bayanhuu Ayushjav, Lidija Injac Stevovic, José Santiago Sequeira Molina, Oye Gureje, Jan Olav Johannessen, Haroon Rashid Chaudhry, Bassam Al‐Ashhab, Aleksander Araszkiewicz, Dan Prelipceanu, Valery Krasnov, Anatoly Bogdanov, Miroslava Jasovic‐Gasic, Livia Vavrusova, Peter Pregelj, Alberto Fernandez Liria, Abdallah Abdelrahman, Pichet Udomratn, Halis Ulas, Peykan Gokalp, Fred N Kigozi, Greg Richardson, None, Reducing the treatment gap for mental disorders: a WPA survey. World Psychiatry. ,vol. 9, pp. 169- 176 ,(2010) , 10.1002/J.2051-5545.2010.TB00305.X
F. Holländare, S. Johnsson, M. Randestad, M. Tillfors, P. Carlbring, G. Andersson, I. Engström, Randomized trial of Internet-based relapse prevention for partially remitted depression. Acta Psychiatrica Scandinavica. ,vol. 124, pp. 285- 294 ,(2011) , 10.1111/J.1600-0447.2011.01698.X
Bernd Löwe, Kurt Kroenke, Wolfgang Herzog, Kerstin Gräfe, Measuring depression outcome with a brief self-report instrument: sensitivity to change of the Patient Health Questionnaire (PHQ-9). Journal of Affective Disorders. ,vol. 81, pp. 61- 66 ,(2004) , 10.1016/S0165-0327(03)00198-8
Tara Donker, Annemieke van Straten, Isaac Marks, Pim Cuijpers, A brief Web-based screening questionnaire for common mental disorders: development and validation. Journal of Medical Internet Research. ,vol. 11, ,(2009) , 10.2196/JMIR.1134
Christina M Gullion, A.John Rush, Toward a generalizable model of symptoms in major depressive disorder Biological Psychiatry. ,vol. 44, pp. 959- 972 ,(1998) , 10.1016/S0006-3223(98)00235-2
A.John Rush, Madhukar H Trivedi, Hicham M Ibrahim, Thomas J Carmody, Bruce Arnow, Daniel N Klein, John C Markowitz, Philip T Ninan, Susan Kornstein, Rachel Manber, Michael E Thase, James H Kocsis, Martin B Keller, The 16-Item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression. Biological Psychiatry. ,vol. 54, pp. 573- 583 ,(2003) , 10.1016/S0006-3223(02)01866-8
L Donkin, I B Hickie, H Christensen, S L Naismith, B Neal, N L Cockayne, N Glozier, Sampling bias in an internet treatment trial for depression. Translational Psychiatry. ,vol. 2, ,(2012) , 10.1038/TP.2012.100
Mar Rivas Rodríguez, Roberto Nuevo, Somnath Chatterji, José Luis Ayuso-Mateos, Definitions and factors associated with subthreshold depressive conditions: a systematic review BMC Psychiatry. ,vol. 12, pp. 181- 181 ,(2012) , 10.1186/1471-244X-12-181
Daniel L. Larsen, C.Clifford Attkisson, William A. Hargreaves, Tuan D. Nguyen, Assessment of client/patient satisfaction: Development of a general scale Evaluation and Program Planning. ,vol. 2, pp. 197- 207 ,(1979) , 10.1016/0149-7189(79)90094-6