The Sensorimotor Basis of Whisker-Guided Anteroposterior Object Localization in Head-Fixed Mice.

摘要: Active tactile perception combines directed motion with sensory signals to generate mental representations of objects in space. Competing models exist for how mice use these determine the precise location along their face. We tested six using behavioral manipulations and statistical learning head-fixed mice. Trained used a whisker locate pole continuous range locations anteroposterior axis. Mice discriminated ≤0.5 mm (<2°) resolution. Their motor program was noisy, adaptive touch, rewarded range. This exploration produced several sets sensorimotor features that could discriminate location. Integration two features, touch count whisking midpoint at simplest model explained behavior best. These results show hyperacute resolution learned strategy minimal set mentally accessible features.