Analysis of racial differences in incidence, survival, and mortality for malignant tumors of the uterine corpus

摘要: BACKGROUND In the United States, incidence rates for malignant tumors of uterine corpus are lower among blacks than whites, whereas mortality higher blacks. Reasons level have been debated. METHODS Using data from Surveillance, Epidemiology, and End Results program, authors compared by histopathologic type (including uterus, not otherwise specified) during period 1992–1998 white Hispanic, black, non-Hispanic patients. The also cumulative relative survival whites other factors, they calculated estimated type-specific rates. RESULTS Overall (per 100,000 woman-years) malignancy was significantly Hispanics (14.04; 95% confidence interval [CI], 13.39–14.72) (15.31; CI, 14.61–16.04) with non-Hispanics (23.43; 23.06–23.81). Compared non-Hispanics, had serous/clear cell carcinoma (rate ratio, 1.85; 1.61–2.12), carcinosarcoma 2.33; 1.99–2.72), sarcoma 1.56; 1.31–1.86). Survival worse in every category ‘usual’ types endometrial adenocarcinoma, stratified stage, grade, age. Rare aggressive tumor accounted 53% blacks, 36% whites. CONCLUSIONS Less favorable outcomes usual adenocarcinoma rare contribute equally to relatively high due cancer black women. Cancer 2003;98:176–86. Published 2003 American Society.* DOI 10.1002/cncr.11484