Lower vitamin-D production from solar ultraviolet-B irradiance may explain some differences in cancer survival rates.

摘要: Black Americans diagnosed with cancer generally have lower survival rates than white Americans, even after adjustment for stage of at time discovery and level treatment received. The hypothesis developed in this work is that these may be due to serum 25-hydroxyvitamin D [25(OH)DI black attributed production vitamin from solar ultraviolet-B (UVB) irradiance darker skin. 50-75% as much 25(OH)D now thought reduce the risk incidence mortality 18 types cancer. To explore hypothesis, data various period 1970-1994 were used indices UVB levels July, smoking, alcohol consumption, urban residence poverty level, all averaged by state, multiple linear regression analyses using ecologic approach. Solar was found significantly inversely correlated breast, colon, esophageal, gastric rectal cancers albeit associations Americans. Smoking consumption also several cancers. Based on results, it seems worthwhile conduct observational, prevention intervention studies further test can death.