Approaches to improve photodynamic therapy of cancer
作者： Malgorzata Firczuk , Magdalena Winiarska , Angelika Szokalska , Malgorzata Jodlowska , Marta Swiech
DOI: 10.2741/3684
关键词: Tumor Cell Biology 、 Cancer research 、 Medicine 、 Cancer 、 Radiation therapy 、 Mechanism of action 、 Photodynamic therapy 、 Immune system 、 Tumor therapy 、 High selectivity 、 General Biochemistry, Genetics and Molecular Biology 、 General Immunology and Microbiology 、 General Medicine
摘要: Photodynamic therapy (PDT) is a clinically approved method of tumor treatment. Its unique mechanism action results from minimal invasiveness and high selectivity towards transformed cells. However, visible light used to excite most photosensitizers has rather limited ability penetrate tissues resulting in insufficient destruction deeply seated malignant Therefore, novel strategies for further potentiation the anticancer effectiveness PDT have been developed. These include combined treatments with surgery, chemo- radiotherapy, targeting cytoprotective mechanisms induced PDT-treated cells, as well attempts aimed at enhancement PDT-mediated antitumor immune response. Moreover, new sources are being Impressive progress nanotechnology understanding cell biology rise hopes improvements this elegant promising cancer
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