The Societal Impact of Single Versus Bilateral Lung Transplantation for Chronic Obstructive Pulmonary Disease
作者： Jeffrey C. Munson , Jason D. Christie , Scott D. Halpern
DOI: 10.1164/RCCM.201104-0695OC
关键词: Lung 、 Transplantation 、 Disease 、 Bilateral lung transplantation 、 Lung transplantation 、 Population 、 Pulmonary disease 、 COPD 、 Medicine 、 Intensive care medicine 、 Internal medicine 、 Critical Care and Intensive Care Medicine 、 Pulmonary and Respiratory Medicine
摘要: Rationale: Bilateral lung transplantation (BLT) improves survival compared with single (SLT) for some individuals chronic obstructive pulmonary disease (COPD). However, it is unclear which strategy optimally uses this scarce societal resource.Objectives: To compare the effect of SLT versus BLT strategies COPD on waitlist outcomes among broader population patients listed transplantation.Methods: We developed a Markov model to simulate transplant using registry data define size, donor frequency, risk death awaiting transplant, and disease- procedure-specific post-transplant survival. then applied 1,000 simulated number under each who received died before transplantation, total survival.Measurements Main Results: Under baseline assumptions, resulted in more transplanted (809 v...
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