Personalized tumor response assessment in the era of molecular medicine: cancer-specific and therapy-specific response criteria to complement pitfalls of RECIST.
作者： Mizuki Nishino , Jyothi P. Jagannathan , Katherine M. Krajewski , Kevin O’Regan , Hiroto Hatabu
DOI: 10.2214/AJR.11.7483
关键词: Personalized medicine 、 Targeted therapy 、 MEDLINE 、 Internal medicine 、 Molecular medicine 、 Clinical trial 、 Medicine 、 Immunology 、 Cancer 、 Response Evaluation Criteria in Solid Tumors 、 Oncology 、 Precision medicine
摘要: OBJECTIVE. The purpose of this article is to review cancer- and therapy-specific tumor response assessment criteria used in clinical trials practice, with illustrative case examples, discuss future directions toward “personalized” assessment. CONCLUSION. Although Response Evaluation Criteria Solid Tumors will remain as the primary generalized for assessment, newer play an important role providing state-of-the-art following molecular targeted therapy contribute personalized cancer care era medicine.
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