Serum ferritin and heart disease: the effect of moderate exercise on stored iron levels in postmenopausal women.

摘要: OBJECTIVE To determine the effect of a moderate exercise regimen on stored iron as measured by serum ferritin in previously sedentary postmenopausal women. DESIGN Randomized assignment to one three groups: five day/week walking group (five-day group, n = 27); (three-day 27) or (control 25). SETTING Community-based intervention. PARTICIPANTS Women who were postmenopausal, over 50 years old, sedentary, not hormone replacement therapy, nonsmokers, physically capable exercising, without clinical signs cardiovascular, pulmonary metabolic disease, and medication that would affect metabolism. In addition, they had neither donated blood nor been transfused within previous 12 months. All participants screened volunteers responded media advertisements. Seventy-nine met these criteria. Results are reported for 56 subjects 17; three-day 19; control 20) completed study. Their mean age was 61.3 +/- 5.8 years. INTERVENTION The five-day walked an average 279 20 171 7 mins/week, respectively. Participants counselled change their dietary intake. MAIN RESULTS Following 24 weeks walking, decreased significantly (P < 0.03), but 0.09) compared with controls. CONCLUSIONS extent physical activity required elicit decrease women determined. This may be clinically significant because increases following menopause excess have cited risk factors coronary artery disease.