Investigation of dissolution rate kinetics of bulk pharmaceutical feed streams within a stirred tank vessel and a twin screw extruder.

作者: Arabella M. McLaughlin , John Robertson , Xiong-Wei Ni

DOI: 10.1080/10837450.2019.1685543

关键词: Flow chemistryWork (thermodynamics)Materials scienceTwin screw extruderMetallurgyDissolutionSTREAMSContinuous manufacturingKinetics

摘要: … of pharmaceuticals … pharmaceutical ingredients (PI) in a mixture of water and IPA. In order for comparison, the same experiments were also carried out in a batch traditional stirred tank …

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