Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling

作者: Phillip Kim , Sharat Singh

DOI:

关键词: Somatic cellReceptor tyrosine kinaseOncogeneOncologyAnticancer drugColorectal cancerDrugInternal medicineTarget signalIn patientMedicine

摘要: The present invention provides methods for selecting a suitable anticancer drug therapy, and identifying predicting response, the treatment of colorectal cancer. also monitoring status cancer how patient with is responding to therapy. further rational selection therapy one or more drugs tailored target signal transduction pathway components dysregulated expression and/or activation levels in patients somatic mutations an oncogene.

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