Genome-wide association study identifies eight loci associated with blood pressure
作者： Christopher Newton-Cheh , Toby Johnson , Vesela Gateva , Martin D Tobin , Murielle Bochud
DOI: 10.1038/NG.361
关键词: Methylenetetrahydrofolate reductase 、 Genome-wide association study 、 Hemodynamics 、 Genetics 、 Population 、 Fibroblast growth factor-5 、 Single-nucleotide polymorphism 、 Blood pressure 、 Biology 、 Genetic association
摘要: Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide. To date, identification of common genetic variants influencing blood pressure has proven …
uq.edu.au
core.ac.uk
elsevier.com
ed.ac.uk
cabdirect.org
bristol.ac.uk
nature.com
sgul.ac.uk 参考文章(83)
Regina M Martin, Chin J Lin, Elaine MF Costa, Maria Leocadia de Oliveira, Alexandre Carrilho, Heloisa Villar, Carlos A Longui, Berenice B Mendonca, None, P450c17 Deficiency in Brazilian Patients: Biochemical Diagnosis through Progesterone Levels Confirmed by CYP17 Genotyping The Journal of Clinical Endocrinology and Metabolism. ,vol. 88, pp. 5739- 5746 ,(2003) , 10.1210/JC.2003-030988
Hans L. Hillege, Wilbert M.T. Janssen, Dick De Zeeuw, Sara-Joan Pinto-Sietsma, Paul E. De Jong, Gerjan Navis, Urinary albumin excretion is associated with renal functional abnormalities in a nondiabetic population. Journal of The American Society of Nephrology. ,vol. 11, pp. 1882- 1888 ,(2000) , 10.1681/ASN.V11101882
Sekar Kathiresan, Olle Melander, Candace Guiducci, Aarti Surti, Noël P Burtt, Mark J Rieder, Gregory M Cooper, Charlotta Roos, Benjamin F Voight, Aki S Havulinna, Björn Wahlstrand, Thomas Hedner, Dolores Corella, E Shyong Tai, Jose M Ordovas, Göran Berglund, Erkki Vartiainen, Pekka Jousilahti, Bo Hedblad, Marja-Riitta Taskinen, Christopher Newton-Cheh, Veikko Salomaa, Leena Peltonen, Leif Groop, David M Altshuler, Marju Orho-Melander, None, Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nature Genetics. ,vol. 40, pp. 189- 197 ,(2008) , 10.1038/NG.75
Jonathan Marchini, Bryan Howie, Simon Myers, Gil McVean, Peter Donnelly, A new multipoint method for genome-wide association studies by imputation of genotypes Nature Genetics. ,vol. 39, pp. 906- 913 ,(2007) , 10.1038/NG2088
H-E Wichmann, Christian Gieger, Thomas Illig, null for the MONICA/KORA Study Group, KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen. ,vol. 67, pp. 26- 30 ,(2005) , 10.1055/S-2005-858226
T. Valle, J. Tuomilehto, R. N. Bergman, S. Ghosh, E. R. Hauser, J. Eriksson, S. J. Nylund, K. Kohtamaki, L. Toivanen, G. Vidgren, E. Tuomilehto-Wolf, C. Ehnholm, J. Blaschak, C. D. Langefeld, R. M. Watanabe, V. Magnuson, D. S. Ally, W. A. Hagopian, E. Ross, T. A. Buchanan, F. Collins, M. Boehnke, Mapping Genes for NIDDM: Design of the Finland—United States Investigation of NIDDM Genetics (FUSION) Study Diabetes Care. ,vol. 21, pp. 949- 958 ,(1998) , 10.2337/DIACARE.21.6.949
Daniel F Gudbjartsson, Unnur S Bjornsdottir, Eva Halapi, Anna Helgadottir, Patrick Sulem, Gudrun M Jonsdottir, Gudmar Thorleifsson, Hafdis Helgadottir, Valgerdur Steinthorsdottir, Hreinn Stefansson, Carolyn Williams, Jennie Hui, John Beilby, Nicole M Warrington, Alan James, Lyle J Palmer, Gerard H Koppelman, Andrea Heinzmann, Marcus Krueger, H Marike Boezen, Amanda Wheatley, Janine Altmuller, Hyoung Doo Shin, Soo-Taek Uh, Hyun Sub Cheong, Brynja Jonsdottir, David Gislason, Choon-Sik Park, Linda M Rasmussen, Celeste Porsbjerg, Jakob W Hansen, Vibeke Backer, Thomas Werge, Christer Janson, Ulla-Britt Jönsson, Maggie CY Ng, Juliana Chan, Wing Yee So, Ronald Ma, Svati H Shah, Christopher B Granger, Arshed A Quyyumi, Allan I Levey, Viola Vaccarino, Muredach P Reilly, Daniel J Rader, Michael JA Williams, Andre M Van Rij, Gregory T Jones, Elisabetta Trabetti, Giovanni Malerba, Pier Franco Pignatti, Attilio Boner, Lydia Pescollderungg, Domenico Girelli, Oliviero Olivieri, Nicola Martinelli, Bjorn R Ludviksson, Dora Ludviksdottir, Gudmundur I Eyjolfsson, David Arnar, Gudmundur Thorgeirsson, Klaus Deichmann, Philip J Thompson, Matthias Wjst, Ian P Hall, Dirkje S Postma, Thorarinn Gislason, Jeffrey Gulcher, Augustine Kong, Ingileif Jonsdottir, Unnur Thorsteinsdottir, Kari Stefansson, None, Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nature Genetics. ,vol. 41, pp. 342- 347 ,(2009) , 10.1038/NG.323
Mark Caulfield, Patricia Munroe, Janine Pembroke, Nilesh Samani, Anna Dominiczak, Morris Brown, John Webster, Peter Ratcliffe, Suzanne O'Shea, Jeanette Papp, Elizabeth Taylor, Richard Dobson, Joanne Knight, Stephen Newhouse, Joel Hooper, Wai Lee, Nick Brain, David Clayton, G Mark Lathrop, Martin Farrall, John Connell, Nigel Benjamin, None, Genome-wide mapping of human loci for essential hypertension The Lancet. ,vol. 361, pp. 2118- 2123 ,(2003) , 10.1016/S0140-6736(03)13722-1
Weizhen Ji, Jia Nee Foo, Brian J O'Roak, Hongyu Zhao, Martin G Larson, David B Simon, Christopher Newton-Cheh, Matthew W State, Daniel Levy, Richard P Lifton, Rare independent mutations in renal salt handling genes contribute to blood pressure variation Nature Genetics. ,vol. 40, pp. 592- 599 ,(2008) , 10.1038/NG.118
Itsik Pe'er, Roman Yelensky, David Altshuler, Mark J. Daly, Estimation of the multiple testing burden for genomewide association studies of nearly all common variants Genetic Epidemiology. ,vol. 32, pp. 381- 385 ,(2008) , 10.1002/GEPI.20303