Efficacy and safety of Zuojin Pill for chronic gastritis: Protocol for a systematic review of randomized controlled trials.

作者: Jianglong Shi , Liyun Liu , Jian Li , Xiaoju Ma , Hairong Qiu

DOI: 10.1097/MD.0000000000021248

关键词: Standard treatmentCochrane LibraryRandomized controlled trialMedicineMEDLINEPillTraditional Chinese medicineInternal medicineAdverse effectQuality of life

摘要: Background Chronic gastritis (CG), as the highest incidence of gastrointestinal diseases, has been gradually increasing around globally. With obvious disadvantages standard treatment, more and people ask traditional Chinese medicine for help in treatment CG. As a compound, Zuojin Pill (ZJP) long history clinical application digestive system diseases. Whereas, neither systematic nor meta-analysis randomized controlled trials explain efficacy safety ZJP treating Thus, we provide protocol to evaluate Methods From beginning December 2019, following electronic databases will be searched studies English or Chinese: Cochrane Library, Embase, PubMed, Web Science, National Knowledge Infrastructure, Biomedical Literature Database, Scientific Journal Wanfang Database. Clinical efficiency, helicobacter pylori infection clearance rate, quality life symptom scores measured primary outcomes. Meta-analysis performed using Stata 15. Outcomes This study current evidence CG treated with from several aspects including life, scores, 1-year recurrent under endoscopy number reported adverse events associated use ZJP. Conclusion The outcomes this review served proof if is effective Prospero registration PROSPERO CRD42020155036.

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