A comparison of patient knowledge of clinical trials and trialist priorities

摘要: BackgroundRecruitment to clinical trials remains poor, and patient knowledge of is one barrier recruitment. To identify deficits, we conducted compared surveys measuring actual trialist priorities for knowledge.MethodsConsenting patients at a tertiary cancer centre answered survey that included• 2 opinion questions about their own willingness join trial, and• 22 questions.Clinical researchers the were asked 13 importance various factors.ResultsOf 126 surveyed, 16% had joined 42% secondary school education or less. The mean correct response rate on was 58%. Higher rates responses associated with lower age (p = 0.05), greater 0.006), prior trial participation < 0.001), agreement strong perceived understanding 0.002). Trialists valued an rationale randomization, placebo, protection, but those particular topics poorly understood by patients.ConclusionsPatient including several concepts ranked important trialists. findings suggest when developing interventions, emphasis should be placed most directly related care, factors such as level considered.