STRATUS optical coherence tomography in unilateral colobomatous excavation of the optic disc and secondary retinoschisis.

作者: Rodrigo Luz Meirelles , Fabio Bom Aggio , Rog�rio Alves Costa , Michel Eid Farah

DOI: 10.1007/S00417-004-0956-1

关键词: Optic diskEpiretinal membraneOptical coherence tomographyAnatomyRetinalFluorescein angiographyRetinoschisisColobomaMedicineOptic disc

摘要: To report the STRATUS optical coherence tomography (STRATUSOCT) findings in a patient with unilateral coloboma-like excavation of optic disc without pit but secondary retinoschisis, as well to discuss possible involved pathophysiologic mechanisms. Observational case report. STRATUSOCT 66-year-old woman retinoschisis encompassing macular region, along evidence mild epiretinal membrane superonasal were evaluated. STRATUSOCT showed signs connection between perineural space and inner retinal layers on temporal border, schisis-like changes extending from macula, cystoid degeneration two lamellar holes their nasal portion. The use third generation OCT afforded an enhanced visualization structures, revealing fluid at several distinct levels, deep superficial breaks apart schisis cavity. We are unaware such previous reports, could find no reference them computerized search using MEDLINE. In addition, our study supports common pathomechanism for development complications pits colobomas.

参考文章(15)
Daniel Krivoy, Ronald Gentile, Jeffrey M Liebmann, Zeev Stegman, Joseph B Walsh, Robert Ritch, None, Imaging Congenital Optic Disc Pits and Associated Maculopathy Using Optical Coherence Tomography Archives of Ophthalmology. ,vol. 114, pp. 165- 170 ,(1996) , 10.1001/ARCHOPHT.1996.01100130159008
Joel S. Schuman, Tamar Pedut-Kloizman, Ellen Hertzmark, Michael R. Hee, Jason R. Wilkins, Jeffery G. Coker, Carmen A. Puliafito, James G. Fujimoto, Eric A. Swanson, Reproducibility of Nerve Fiber Layer Thickness Measurements Using Optical Coherence Tomography Ophthalmology. ,vol. 103, pp. 1889- 1898 ,(1996) , 10.1016/S0161-6420(96)30410-7
Gary C. Brown, Jerry A. Shields, Richard E. Goldberg, Congenital Pits of the Optic Nerve Head: II. Clinical Studies in Humans Ophthalmology. ,vol. 87, pp. 51- 65 ,(1980) , 10.1016/S0161-6420(80)35278-0
Eytan Z Blumenthal, Julia M Williams, Robert N Weinreb, Christopher A Girkin, Charles C Berry, Linda M Zangwill, Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography Ophthalmology. ,vol. 107, pp. 2278- 2282 ,(2000) , 10.1016/S0161-6420(00)00341-9
Harvey Lincoff, Robert Lopez, Ingrid Kreissig, Lawrence Yannuzzi, Morton Cox, Thomas Burton, None, Retinoschisis Associated With Optic Nerve Pits Archives of Ophthalmology. ,vol. 106, pp. 61- 67 ,(1988) , 10.1001/ARCHOPHT.1988.01060130067030
Bryan K. Rutledge, Carmen A. Puliafito, Jay S. Duker, Michael R. Hee, Morton S. Cox, Optical Coherence Tomography of Macular Lesions Associated with Optic Nerve Head Pits Ophthalmology. ,vol. 103, pp. 1047- 1053 ,(1996) , 10.1016/S0161-6420(96)30568-X
J. Savell, J. R. Cook, Optic nerve colobomas of autosomal-dominant heredity. Archives of Ophthalmology. ,vol. 94, pp. 395- 400 ,(1976) , 10.1001/ARCHOPHT.1976.03910030183002
David J Apple, Maurice F Rabb, Patricia M Walsh, None, Congenital anomalies of the optic disc. Survey of Ophthalmology. ,vol. 27, pp. 3- 41 ,(1982) , 10.1016/0039-6257(82)90111-4
T. ABE, N. YAMADA, K. ABE, M. TAMAI, Corneal endothelial changes and trinucleotide repeat expansion of DRPLA gene British Journal of Ophthalmology. ,vol. 83, pp. 124- 125 ,(1999) , 10.1136/BJO.83.1.123C