Defective Extracellular Matrix Reorganization by Chronic Wound Fibroblasts is Associated with Alterations in TIMP-1, TIMP-2, and MMP-2 Activity
作者： Helen Cook , Phil Stephens , K. June Davies , David W. Thomas , Keith G. Harding
DOI: 10.1046/J.1523-1747.2000.00044.X
关键词: Chronic wound 、 Matrix metalloproteinase 、 Fibroblast 、 Gelatinase A 、 Inflammation 、 Type I collagen 、 Pathology 、 Extracellular matrix 、 Internal medicine 、 Matrix (biology) 、 Endocrinology 、 Chemistry
摘要: … production of tissue inhibitors of metalloproteinase-1 and -2 by the chronic wound fibroblasts (p <0.05). Increased production of tissue inhibitors of metalloproteinases in chronic wound …
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