Factors contributing to spontaneous Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected macaques.

作者: Inderpal Singh , Wenjun Li , Margo Woods , Angela Carville , Saul Tzipori

DOI: 10.1111/J.1600-0684.2006.00181.X

关键词: CohortAcquired immunodeficiency syndrome (AIDS)MicronutrientViral loadBiologyPlaceboVitaminSimian immunodeficiency virusVirologyEnterocytozoon bieneusiImmunology

摘要: Background  A cohort of SIV-infected macaques had been used to investigate the effect dietary supplement, immune status, SIV/AIDS disease progression and serum micronutrients levels on spontaneous acquisition Enterocytozoon bieneusi infection in macaques. Methods  Twenty-four were randomized into 2 groups. One group received a vitamin/mineral supplementation second placebo. Both groups examined for E. infection. Results  more prone acquire with SIV/AIDS, increased shedding infectious spores was directly associated decreased CD4 lymphocyte circulating SIV, both supplemented unsupplemented animals. Dietary supplementation, body composition factors however no association these animals. Conclusions  Acquisition is related SIV progression, counts viral load but independent changes micronutrient levels.

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