Piperidine-Based Spiro-Fused Biheterocycles
作者： Ruben Vardanyan
DOI: 10.1016/B978-0-12-805157-3.00009-0
关键词: Fenspiride 、 Pharmacology 、 Fluspirilene 、 Anxiolytic 、 Piperidine 、 Chemistry 、 Sedative 、 Spiperone 、 Pazinaclone 、 Antipsychotic
摘要: This chapter describes methods of synthesis, pharmacological properties and the use derivatives piperidine-based spiro-fused biheterocycles that are represented on pharmaceutical market with six drugs: typical antipsychotics spiperone, fluspirilene mosapramine, three other drugs diverse spiro-cyclic structure: bronchodilator fenspiride, a neuroleptic agent clospirazine, an investigational sedative anxiolytic drug, pazinaclone.
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