Finger clubbing in inflammatory bowel disease: its prevalence and pathogenesis.

作者: G Kitis , H Thompson , R N Allan

DOI: 10.1136/BMJ.2.6194.825

关键词: RectumInflammatory bowel diseasePathogenesisMedicineSpinal osteoarthropathyFibrosisGastroenterologyPathologyUlcerative colitisInternal medicineColitisProctitis

摘要: Finger clubbing, measured objectively by using the hyponychial angle, was present in 75 out of 200 (38%) patients with Crohn's disease, 15 103 (15%) ulcerative colitis, and two 24 (8%) proctitis. In disease colitis angle significantly correlated both activity extent fibrosis resected specimens from 47 surgically treated patients. The prevalence finger clubbing macroscopic within area gut innervated vagus nerve higher than that whom confined to distal colon rectum. tended regress after resection disease. It is concluded commoner colitis. focal stimuli for include mucosal inflammatory change mediated possibly other autonomic pathways acting as afferent arc a finger-clubbing reflex.

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