Tranexamic acid use in high-risk blood transfusion patients undergoing total hip replacement: a randomised controlled trial

作者: Osamu S Kimura , Emílio HCA Freitas , Maria EL Duarte , Amanda S Cavalcanti , Marco BC Fernandes

DOI: 10.1177/1120700019889947

关键词: Tranexamic acidAnesthesiaTotal hip arthroplastyIntravenous doseIn patientRandomized controlled trialTotal hip replacementMedicineBlood transfusionBlood loss

摘要: Introduction:We hypothesised that a single preoperative intravenous dose of tranexamic acid (TXA) is effective in patients who undergo total hip arthroplasty (THA) and are at high risk blood tra...

参考文章(33)
Duy L Phan, Joseph B Rinehart, Ran Schwarzkopf, Can tranexamic acid change preoperative anemia management during total joint arthroplasty World journal of orthopedics. ,vol. 6, pp. 521- 527 ,(2015) , 10.5312/WJO.V6.I7.521
James A. Browne, Farshad Adib, Thomas E. Brown, Wendy M. Novicoff, Transfusion rates are increasing following total hip arthroplasty: risk factors and outcomes. Journal of Arthroplasty. ,vol. 28, pp. 34- 37 ,(2013) , 10.1016/J.ARTH.2013.03.035
Daniel R. Whiting, Blake P. Gillette, Christopher Duncan, Hugh Smith, Mark W. Pagnano, Rafael J. Sierra, Preliminary Results Suggest Tranexamic Acid is Safe and Effective in Arthroplasty Patients with Severe Comorbidities Clinical Orthopaedics and Related Research®. ,vol. 472, pp. 66- 72 ,(2014) , 10.1007/S11999-013-3134-0
Jai Hyung Park, Mohammad R Rasouli, S.M Javad Mortazavi, Anthony T Tokarski, Mitchell G Maltenfort, Javad Parvizi, Predictors of perioperative blood loss in total joint arthroplasty. Journal of Bone and Joint Surgery, American Volume. ,vol. 95, pp. 1777- 1783 ,(2013) , 10.2106/JBJS.L.01335
JEFFREY B. GROSS, Estimating allowable blood loss: corrected for dilution. Anesthesiology. ,vol. 58, pp. 277- 280 ,(1983) , 10.1097/00000542-198303000-00016
Harry Lemmens, Donald Bernstein, Jay Brodsky, Estimating blood volume in obese and morbidly obese patients. Obesity Surgery. ,vol. 16, pp. 773- 776 ,(2006) , 10.1381/096089206777346673
Joshua J Jacobs, Michael A Mont, Kevin John Bozic, Craig J Della Valle, Stuart Barry Goodman, Courtland G Lewis, Adolph Chick J Yates, Lisa N Boggio, William C Watters, Charles M Turkelson, Janet L Wies, Patrick Sluka, Kristin Hitchcock, American Academy of Orthopaedic Surgeons Clinical Practice Guideline on: Preventing Venous Thromboembolic Disease in Patients Undergoing Elective Hip and Knee Arthroplasty Journal of Bone and Joint Surgery, American Volume. ,vol. 94, pp. 746- 747 ,(2012) , 10.2106/JBJS.9408.EBO746
Xin-die Zhou, Li-jiang Tao, Jin Li, Li-dong Wu, Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials Archives of Orthopaedic and Trauma Surgery. ,vol. 133, pp. 1017- 1027 ,(2013) , 10.1007/S00402-013-1761-2