Optical Image-Guided Cancer Surgery: Challenges and Limitations

作者: Stijn Keereweer , Pieter B.A.A. Van Driel , Thomas J.A. Snoeks , Jeroen D.F. Kerrebijn , Robert J. Baatenburg de Jong

DOI: 10.1158/1078-0432.CCR-12-3598

关键词: Tumor tissueRadical resectionOncologic SurgeonOptical imageOptical imagingSurgeryCancer surgeryComplete resectionMedical physicsMedicineImproved survivalCancer researchOncology

摘要: Optical image-guided cancer surgery is a promising technique to adequately determine tumor margins by tumor-specific targeting, potentially resulting in complete resection of tissue with improved survival. However, identification the photons coming from fluorescent contrast agent complicated autofluorescence, optical properties, and accurate targeting agents imaging systems. All these factors have an important influence on image that presented surgeon. Considering clinical consequences at stake, it prerequisite answer questions are essential for What how can improve patient care? should oncologic surgeon know about fundamental principles understand which conclusions be drawn images? And do limitations decision making? This article discusses provides clear overview basic practical applications. Although there intrinsic capacity technique, when technical surgical possibilities considered, very powerful intraoperative tool guiding future toward radical optimal results.

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