The prevalence, course, and characteristics of chronic anemia after heart and lung transplantation.

摘要: A retrospective study of the 99 surviving heart and lung transplant (HLT) recipients at one center showed that 31% had significant anemia (hemoglobin less than 100g/L) six months after transplantation. Chronic persisted in 18% HLT two years posttransplantation. similar 100 no unexplained anemic patients. The prevalence was unrelated to original diagnosis, immunosuppression, or acute rejection. All appeared be unduly sensitive myelosuppressive effects azathioprine. Detailed studies 16 representative patients a normochromic, anisocytotic with normal reticulocyte counts, B12 folate levels, haptoglobin levels appropriate erythropoietin levels--but increased ESRs, low/normal iron total binding capacity, raised ferritin autoantibodies 4 (25%). Bone marrow aspirates 10 dyshemopoiesis out proportion degree colonies activated lymphoid cells. cause for this appears combination chronic disease dyshemopoiesis, both uncertain etiology.