Kidney disease after heart and lung transplantation
作者： R.D. Bloom , A.M. Doyle
DOI: 10.1111/J.1600-6143.2006.01248.X
关键词:
摘要: Kidney disease is a commonly recognized complication of heart and lung transplantation associated with increased morbidity mortality. While the spectrum kidney in this population wide-ranging, studies indicate that between 3% 10% these patients will ultimately develop end-stage renal (ESRD). This review examines risk factors for both acute chronic injury, particular emphasis on role calcineurin inhibitor-mediated nephrotoxicity settings. Against background current National Foundation Disease Outcomes Quality Initiative (KDOQI) guidelines, we have further considered recommended appropriate strategies long-term management disease-related manifestations transplant recipients. Specific aspects addressed include retarding progressive injury minimizing nephrotoxicity, as well treatment hypertension, hyperlipidemia anemia. Finally, advanced disease, replacement therapy options are discussed. Based impact outcomes recipients, advocate early referral to nephrologist displaying evidence significant dysfunction.
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