Comparison between Crystalline Dihydrotachysterol and Calciferol in Patients Requiring Pharmacologic Vitamin D Therapy

作者: Harold E. Harrison , Fima Lifshitz , Robert M. Blizzard

DOI: 10.1056/NEJM196704202761603

关键词: Blood serumErgocalciferolEndocrinologyVitaminVitamin D and neurologyRicketsCholecalciferolMedicineInternal medicineDihydrotachysterolHypercalcaemiaGeneral Medicine

摘要: PATIENTS requiring pharmacologic amounts of vitamin D have usually been treated with ergocalciferol (vitamin D2) although cholecalciferol D3) and dihydrotachysterol also used. Dihydrotachysterol, like ergocalciferol, is a product irradiation ergosterol was isolated by Holtz Schreiber,1 who were searching for steroid more effective than in the treatment hypocalcemic states. The pharmaceutical preparation AT10 (Hytakerol), assayed terms assumed content, actually mixture steroids dihydrovitamin D2II, an isomer dihydrotachysterol, as chief component.2 This has shown . . .

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