Vitamin D resistance in magnesium deficiency.

摘要: Four patients with gastrointestinal disorders, and one patient chronic alcoholism presented both hypocalcemia hypomagnesemia. Pharmacological doses of either ergocalciferol or dihydrotachysterol did not correct the except in who had a minimal rise serum calcium. Parathormone levels were high three exogenous parathormone given to fourth subject failed elicit calcium, implying impairment calcemic response parathormone. Magnesium repletion simultaneously corrected hypomagnesemia hypocalcemia. Balance data suggested that calcium was part, at least, due increased mobilization minerals from bone. While mechanism remains speculative, it appears magnesium facilitates release bone presence adequate amounts vitamin D