Structural brain abnormalities in patients with schizophrenia and their healthy siblings.
作者： Wouter G Staal , Hilleke E Hulshoff Pol , Hugo G Schnack , Mechteld LC Hoogendoorn , Korn 纯 Jellema
DOI: 10.1176/APPI.AJP.157.3.416
关键词: Central nervous system 、 Neuroscience 、 Psychology 、 Third ventricle 、 Psychosis 、 Anatomy 、 Cerebrum 、 Frontal lobe 、 Caudate nucleus 、 Magnetic resonance imaging 、 Parahippocampal gyrus
摘要: OBJECTIVE: The authors sought to investigate the contribution of genotype on structural brain abnormalities in schizophrenia. METHOD: Intracranial volumes and cerebrum, white gray matter, lateral third ventricles, frontal lobes, caudate nucleus, amygdala, hippocampus, parahippocampal gyrus, cerebellum were measured 32 same-sex siblings discordant for schizophrenia matched comparison subjects by means magnetic resonance imaging. RESULTS: Third ventricle did not differ between schizophrenic patients their healthy siblings. However, both had higher than subjects. lower cerebrum subjects, whereas volume significantly from or Additionally, with displayed a reduction lobe matter increase caudate...
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