Hypothalamic enkephalin neurones may regulate the neurohypophysis.
作者： JEAN ROSSIER , ELENA BATTENBERG , QUENTIN PITTMAN , ALEJANDRO BAYON , LEONARD KODA
DOI: 10.1038/277653A0
关键词: Endocrinology 、 Neurosecretion 、 Enkephalin 、 Hypothalamus 、 Neurointermediate lobe 、 Chemistry 、 Internal medicine 、 Pentapeptide repeat 、 Lobe 、 Brain region 、 Globus pallidus
摘要: WE have previously reported that significant amounts of immunoreactive (ir)-Leu5-enkephalin were present in extracts the neurointermediate lobe rat pituitary1. Negligible pentapeptide detected anterior lobe. In these assays, concentration Leu5-enkephalin was higher than globus pallidus, brain region to contain densest enkephalinergic innervation2. The high content (ir)-Leu-enkephalin pituitary led us further investigation its distribution and possible function. We report here (ir)-enkephalins are concentrated nerve fibres projecting from hypothalamus pars nervosa this pathway may be involved regulation neurohypophysial neurosecretion.
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