Buccal Drug Delivery Systems
作者： N. Chidambaram , A. K. Srivatsava
DOI: 10.3109/03639049509069802
关键词: Buccal mucosa 、 Dosage form 、 Intravenous route 、 Drug 、 Oral mucosa 、 In vivo 、 Medicine 、 Pharmacology 、 Drug delivery 、 Buccal administration
摘要: AbstractBuccal administration offers certain unique advantages for the drugs which cannot be easily or efficiently administered by oral intravenous route. However, transbucccal delivery receiived relatively little attention and few well-controlled studies of buccal mucosa permeability have been conducted. The provides a protective covering underlying tissue, being as barrier microorganisms toxins. This article extensively reviews histology mucosa, permeation (both invitro in vivo) drug system, their development various types techniques devices available through mucosa.
informapharmascience.com参考文章(76)
Hans P. Merkle, Reinhold Anders, Jürgen Sandow, Werner Schurr, Drug Delivery of Peptides: The Buccal Route Springer, Boston, MA. pp. 159- 175 ,(1986) , 10.1007/978-1-4757-9960-6_13
Yuji Kurosaki, Toshihito Takatori, Hidekatsu Nishimura, Taiji Nakayama, Toshikiro Kimura, Regional variation in oral mucosal drug absorption: permeability and degree of keratinization in hamster oral cavity. Pharmaceutical Research. ,vol. 8, pp. 1297- 1301 ,(1991) , 10.1023/A:1015812114843
D. Attwood, A. T. Florence, Biological implications of surfactant presence in formulations Springer Netherlands. pp. 388- 468 ,(1983) , 10.1007/978-94-009-5775-6_7
Klaus Wolff, Elisabeth Schreiner, [Uptake, intracellular transport, and degradation of exogenous protein by keratinocytes. Electron microscopy and cytochemical study using peroxidase as a tracer substance]. Archiv für klinische und experimentelle Dermatologie. ,vol. 235, pp. 203- 220 ,(1969) , 10.1007/BF00501845
Richard T. Tregear, Physical functions of skin Academic Press. ,(1966)
Christopher Alan Squier, Julia Meyer, Current concepts of the histology of oral mucosa Thomas. ,(1971)
J. T. Dingle, Lysosomes: A laboratory handbook ,(1972)
E Shefter, B J Aungst, N J Rogers, Comparison of nasal, rectal, buccal, sublingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter. Journal of Pharmacology and Experimental Therapeutics. ,vol. 244, pp. 23- 27 ,(1988)
D. Adams, Penetration of water through human and rabbit oral mucosa in vitro. Archives of Oral Biology. ,vol. 19, pp. 865- 872 ,(1974) , 10.1016/0003-9969(74)90048-X
MASAMI ISHIDA, NAOKI NAMBU, TSUNEJI NAGAI, Mucosal dosage form of lidocaine for toothache using hydroxypropyl cellulose and Carbopol. Chemical & Pharmaceutical Bulletin. ,vol. 30, pp. 980- 984 ,(1982) , 10.1248/CPB.30.980