作者: Frank Vitzthum
DOI:
关键词: Analyte 、 Chromatography 、 Molecular switch 、 Nucleic acid 、 Quantitative determination 、 Substrate (chemistry) 、 Derivative (chemistry) 、 Chemistry 、 Catalysis
摘要: The invention relates to analytical test systems and methods, in which molecular switches are used for the qualitative quantitative determination of analytes a sample, have broad application by means selection switch suitable analyte. comprises probe, preferably nucleic acid or derivative, coupled catalytic component, an enzyme. analyte induces conformation change alters accessibility substrate probe components turnover, corresponding activity, is measured.