Evaluation of a Red Cell Agglutination Test for Detection of Australia Antigen (HB Ag)

作者: Kathryn H. Germain , Sherry K. Sturdivant , Wilton A. Rightsel

DOI: 10.1128/AM.25.4.524-527.1973

关键词: Hepatitis B AntigensAntigenHighly sensitiveVirologyImmune seraRed cell agglutinationHemagglutination testsMolecular biologyHepatitis BChemistryRadioimmunoassayGeneral Pharmacology, Toxicology and PharmaceuticsGeneral Biochemistry, Genetics and Molecular BiologyGeneral Immunology and MicrobiologyGeneral Medicine

摘要: An investigational red cell agglutination (RCA) test was evaluated for sensitivity in detecting and titering hepatitis B antigen (HB Ag) comparison with two counterelectrophoresis (CEP) systems a solid-phase radioimmunoassay (RIA). The RCA procedure found to be significantly more sensitive than the CEP methods compares favorably RIA, even lower concentrations of HB Ag. Since can completed 2 3 h requires relatively inexpensive equipment, it offers highly rapid suitable use blood banks screen donors or detect low levels serum patients.

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