Morphological and functional correlates of synchronous beating between embryonic heart cell aggregates and layers.
作者： Eva B. Griepp , John H. Peacock , Merton R. Bernfield , Jean-Paul Revel
DOI: 10.1016/0014-4827(78)90367-1
关键词: Cell coupling 、 Beat (acoustics) 、 Gap junction 、 Anatomy 、 Biology 、 Embryonic heart 、 Biophysics 、 Cell 、 Intracellular 、 Microelectrode
摘要: We have examined correlations between morphological and functional evidence of cell coupling aggregates beating embryonic heart cells underlying layers. Synchronously aggregate-layer pairs were compared with asynchronous pairs. Intracellular microelectrode studies demonstrated that asynchronously aggregate-layers could not be induced to beat synchronously by electrical stimulation the aggregate, whereas 86% synchronous instances showed propagation stimulating current pulses from aggregate layer. By freeze fracture we found significant differences both in number total area gap junctions interfaces preparations. The data suggest is a reliable indication effective ionic coupling, requires certain junction/cell.
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