Learning and Memory in Addiction

作者: Stephanie A. Carmack , George F Koob , Stephan G. Anagnostaras

DOI: 10.1016/B978-0-12-809324-5.21101-2

关键词: AddictionDrug seekingPsychiatryDrugCravingPsychologyChronic diseaseOpioidPsychotherapistPsychological dependenceAbstinence Syndrome

摘要: Drug addiction is a chronic disease characterized by cyclical pattern of intense drug seeking and use, quitting, the emergence an abstinence syndrome, cravings, relapse. As seeking, craving, relapse occur when no longer physiologically active, overall hypothesis that persists as memory or memory-like process long after exposure has become widely accepted. The aim this chapter to review ways in which learning have been implicated both behavioral phenomenology neurobiology addiction.

参考文章(225)
Mann Aj, Rawson Ra, McCann Mj, Obert Jl, Cocaine treatment outcome: cocaine use following inpatient, outpatient, and no treatment. NIDA research monograph. ,vol. 67, pp. 271- ,(1986)
Steven M. Mirin, Roger E. Meyer, The Heroin Stimulus : Implications for a Theory of Addiction ,(2012)
Elise M. Weerts, Amy K. Goodwin, Barbara J. Kaminski, Robert D. Hienz, Environmental cues, alcohol seeking, and consumption in baboons: effects of response requirement and duration of alcohol abstinence. Alcoholism: Clinical and Experimental Research. ,vol. 30, pp. 2026- 2036 ,(2006) , 10.1111/J.1530-0277.2006.00249.X
Rutsuko Ito, Jeffrey W. Dalley, Trevor W. Robbins, Barry J. Everitt, Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue. The Journal of Neuroscience. ,vol. 22, pp. 6247- 6253 ,(2002) , 10.1523/JNEUROSCI.22-14-06247.2002
Ashley North, Jarod Swant, Michael F. Salvatore, Joyonna Gamble-george, Petra Prins, Brittany Butler, Mukul K. Mittal, Rebecca Heltsley, John T. Clark, Habibeh Khoshbouei, Chronic methamphetamine exposure produces a delayed, long‐lasting memory deficit Synapse. ,vol. 67, pp. 245- 257 ,(2013) , 10.1002/SYN.21635
David W. Self, Lisa M. Genova, Bruce T. Hope, William J. Barnhart, Jennifer J. Spencer, Eric J. Nestler, Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior The Journal of Neuroscience. ,vol. 18, pp. 1848- 1859 ,(1998) , 10.1523/JNEUROSCI.18-05-01848.1998
Lee Hogarth, Bernard W. Balleine, Laura H. Corbit, Simon Killcross, Associative learning mechanisms underpinning the transition from recreational drug use to addiction. Annals of the New York Academy of Sciences. ,vol. 1282, pp. 12- 24 ,(2013) , 10.1111/J.1749-6632.2012.06768.X
Trevor W. Robbins, Barry J. Everitt, Drug addiction: bad habits add up. Nature. ,vol. 398, pp. 567- 570 ,(1999) , 10.1038/19208
Mark A. Ungless, Jennifer L. Whistler, Robert C. Malenka, Antonello Bonci, Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons Nature. ,vol. 411, pp. 583- 587 ,(2001) , 10.1038/35079077