作者: Bogdali M. Anna , Antoszczyk Grazyna , Dyga Wojciech , Obtulowicz Aleksander , Bialecka Anna
DOI: 10.1016/J.JTEMB.2015.06.009
关键词: Atopic dermatitis 、 Case-control study 、 Medicine 、 ELISPOT 、 Immunoglobulin E 、 Immunology 、 Enterotoxin 、 Nickel allergy 、 Staphylococcus aureus 、 Staphylococcal infections
摘要: Abstract Background The increase of nickel air pollution is supposed to frequent side effects action related virulence potential Staphylococcus aureus in patients with allergy atopic dermatitis. goal was investigate the relationship between and infection by S. Methods Nickel confirmed excluded healthy volunteers using patch testing. Infection tested use API Staph system. specific IgE for staphylococcal enterotoxin A B were measured. Secretion IFN-g, IL-2, IL-13 PBMC under sulfate enterotoxins stimulations studied ELISpot. Results We found increased number infections comparison without allergy. elevated secretion IL-2 stimulation vitro exclusively infected . Conclusions Our data suggest that are linked