Nickel allergy and relationship with Staphylococcus aureus in atopic dermatitis

作者: Bogdali M. Anna , Antoszczyk Grazyna , Dyga Wojciech , Obtulowicz Aleksander , Bialecka Anna

DOI: 10.1016/J.JTEMB.2015.06.009

关键词: Atopic dermatitisCase-control studyMedicineELISPOTImmunoglobulin EImmunologyEnterotoxinNickel allergyStaphylococcus aureusStaphylococcal infections

摘要: Abstract Background The increase of nickel air pollution is supposed to frequent side effects action related virulence potential Staphylococcus aureus in patients with allergy atopic dermatitis. goal was investigate the relationship between and infection by S. Methods Nickel confirmed excluded healthy volunteers using patch testing. Infection tested use API Staph system. specific IgE for staphylococcal enterotoxin A B were measured. Secretion IFN-g, IL-2, IL-13 PBMC under sulfate enterotoxins stimulations studied ELISpot. Results We found increased number infections comparison without allergy. elevated secretion IL-2 stimulation vitro exclusively infected . Conclusions Our data suggest that are linked

参考文章(28)
Grazyna Antoszczyk, Anna Wojas-Pelc, Aleksander Obtułowicz, Krystyna Obtułowicz, Jadwiga Bogdaszewska-Czabanowska, Katarzyna Szmigiel-Michalak, Nickel allergy in contact and atopic dermatitis Przegla̧d lekarski. ,vol. 60, pp. 334- ,(2003)
Hannah J. Gould, Pooja Takhar, Helen E. Harries, Elfy Chevretton, Brian J. Sutton, The allergic march from Staphylococcus aureus superantigens to immunoglobulin E. Chemical immunology and allergy. ,vol. 93, pp. 106- 136 ,(2007) , 10.1159/000100861
S.-W. Hong, M.-R. Kim, E.-Y. Lee, J. H. Kim, Y.-S. Kim, S. G. Jeon, J.-M. Yang, B.-J. Lee, B.-Y. Pyun, Y. S. Gho, Y.-K. Kim, Extracellular vesicles derived from Staphylococcus aureus induce atopic dermatitis-like skin inflammation. Allergy. ,vol. 66, pp. 351- 359 ,(2011) , 10.1111/J.1398-9995.2010.02483.X
Laetitia Remy, Marie Carrière, Aurélie Derré-Bobillot, Cécilia Martini, Maurizio Sanguinetti, Elise Borezée-Durant, TheStaphylococcus aureusOpp1 ABC transporter imports nickel and cobalt in zinc-depleted conditions and contributes to virulence Molecular Microbiology. ,vol. 87, pp. 730- 743 ,(2013) , 10.1111/MMI.12126
Mark Boguniewicz, Donald Y. M. Leung, Atopic dermatitis: a disease of altered skin barrier and immune dysregulation Immunological Reviews. ,vol. 242, pp. 233- 246 ,(2011) , 10.1111/J.1600-065X.2011.01027.X
Rachel M. McLoughlin, Jean C. Lee, Dennis L. Kasper, Arthur O. Tzianabos, IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection. Journal of Immunology. ,vol. 181, pp. 1323- 1332 ,(2008) , 10.4049/JIMMUNOL.181.2.1323
Kathy Lynn Smith, David A. Lawrence, Immunomodulation of in vitro antigen presentation by cations Toxicology and Applied Pharmacology. ,vol. 96, pp. 476- 484 ,(1988) , 10.1016/0041-008X(88)90007-5
Anne M. Brauweiler, Lianghua Bin, Byung Eui Kim, Michiko K. Oyoshi, Raif S. Geha, Elena Goleva, Donald Y.M. Leung, Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin–induced keratinocyte death The Journal of Allergy and Clinical Immunology. ,vol. 131, pp. 421- 427 ,(2013) , 10.1016/J.JACI.2012.10.030
Natalija Novak, Hansjörg Baurecht, Torsten Schäfer, Elke Rodriguez, Stefan Wagenpfeil, Norman Klopp, Joachim Heinrich, Heidrun Behrendt, Johannes Ring, Erich Wichmann, Thomas Illig, Stephan Weidinger, Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel. Journal of Investigative Dermatology. ,vol. 128, pp. 1430- 1435 ,(2008) , 10.1038/SJ.JID.5701190