A mouse model for EML4-ALK-positive lung cancer

J. A. Engelman, K. Zejnullahu, T. Mitsudomi, Y. Song, C. Hyland, J. O. Park, N. Lindeman, C.-M. Gale, X. Zhao, J. Christensen, T. Kosaka, A. J. Holmes, A. M. Rogers, F. Cappuzzo, T. Mok, C. Lee, B. E. Johnson, L. C. Cantley, P. A. Janne, MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling Science. ,vol. 316, pp. 1039- 1043 ,(2007) , 10.1126/SCIENCE.1141478

Wenrui Duan, Haiming Ding, Mark A Subler, Wei-Guo Zhu, Huiming Zhang, Gary D Stoner, Jolene J Windle, Gregory A Otterson, Miguel A Villalona-Calero, Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice Oncogene. ,vol. 21, pp. 7831- 7838 ,(2002) , 10.1038/SJ.ONC.1205909

U. McDermott, S. V. Sharma, L. Dowell, P. Greninger, C. Montagut, J. Lamb, H. Archibald, R. Raudales, A. Tam, D. Lee, S. M. Rothenberg, J. G. Supko, R. Sordella, L. E. Ulkus, A. J. Iafrate, S. Maheswaran, C. N. Njauw, H. Tsao, L. Drew, J. H. Hanke, X.-J. Ma, M. G. Erlander, N. S. Gray, D. A. Haber, J. Settleman, Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 19936- 19941 ,(2007) , 10.1073/PNAS.0707498104

Young Lim Choi, Ruri Kaneda, Tomoaki Wada, Shin-ichiro Fujiwara, Manabu Soda, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Munehiro Enomoto, Shuji Takada, Yoshihiro Yamashita, Hiroyuki Mano, None, Identification of a constitutively active mutant of JAK3 by retroviral expression screening. Leukemia Research. ,vol. 31, pp. 203- 209 ,(2007) , 10.1016/J.LEUKRES.2006.05.006

A. V. Galkin, J. S. Melnick, S. Kim, T. L. Hood, N. Li, L. Li, G. Xia, R. Steensma, G. Chopiuk, J. Jiang, Y. Wan, P. Ding, Y. Liu, F. Sun, P. G. Schultz, N. S. Gray, M. Warmuth, Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 270- 275 ,(2007) , 10.1073/PNAS.0609412103

Danan Li, Takeshi Shimamura, Hongbin Ji, Liang Chen, Henry J. Haringsma, Kate McNamara, Mei-Chih Liang, Samanthi A. Perera, Sara Zaghlul, Christa L. Borgman, Shigeto Kubo, Masaya Takahashi, Yanping Sun, Lucian R. Chirieac, Robert F. Padera, Neal I. Lindeman, Pasi A. Jänne, Roman K. Thomas, Matthew L. Meyerson, Michael J. Eck, Jeffrey A. Engelman, Geoffrey I. Shapiro, Kwok-Kin Wong, Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy Cancer Cell. ,vol. 12, pp. 81- 93 ,(2007) , 10.1016/J.CCR.2007.06.005

Anil Mishra, Timothy E. Weaver, David C. Beck, Marc E. Rothenberg, Interleukin-5-mediated Allergic Airway Inflammation Inhibits the Human Surfactant Protein C Promoter in Transgenic Mice Journal of Biological Chemistry. ,vol. 276, pp. 8453- 8459 ,(2001) , 10.1074/JBC.M009481200

Young Lim Choi, Kengo Takeuchi, Manabu Soda, Kentaro Inamura, Yuki Togashi, Satoko Hatano, Munehiro Enomoto, Toru Hamada, Hidenori Haruta, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Toshihide Ueno, Shuji Takada, Yoshihiro Yamashita, Yukihiko Sugiyama, Yuichi Ishikawa, Hiroyuki Mano, Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non–Small Cell Lung Cancer Cancer Research. ,vol. 68, pp. 4971- 4976 ,(2008) , 10.1158/0008-5472.CAN-07-6158

Joseph R. Testa, Zemin Liu, Madelyn Feder, Daphne W. Bell, Binaifer Balsara, Cheng Jin Quan, Taguchi Takahiro, Advances in the analysis of chromosome alterations in human lung carcinomas Cancer Genetics and Cytogenetics. ,vol. 95, pp. 20- 32 ,(1997) , 10.1016/S0165-4608(96)00337-8

Joan H. Schiller, David Harrington, Chandra P. Belani, Corey Langer, Alan Sandler, James Krook, Junming Zhu, David H. Johnson, Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. The New England Journal of Medicine. ,vol. 346, pp. 92- 98 ,(2002) , 10.1056/NEJMOA011954