Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non–Small Cell Lung Cancer
作者： Young Lim Choi , Kengo Takeuchi , Manabu Soda , Kentaro Inamura , Yuki Togashi
DOI: 10.1158/0008-5472.CAN-07-6158
关键词:
摘要: … lung cancer cells that express endogenous EML4-ALK variant 3. The human lung cancer cell line NCI-H2228 expresses EML4-ALK … EML4-ALK is essential for the growth of cancer cells …
aacrjournals.org
sci-hub.se 
researchgate.net 参考文章(20)
L L Lanier, A Miyajima, G P Nolan, A Shibuya, Y Morikawa, T Kitamura, J Phillips, S Kinoshita, M Onishi, D M Gorman, Applications of retrovirus-mediated expression cloning. Experimental Hematology. ,vol. 24, pp. 324- 329 ,(1996)
A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, C. Smigal, M. J. Thun, Cancer statistics, 2006. CA: A Cancer Journal for Clinicians. ,vol. 56, pp. 106- 130 ,(2006) , 10.3322/CANJCLIN.56.2.106
Toshikazu Takeshita, Tomikazu Arita, Masaya Higuchi, Hironobu Asao, Kazuhiro Endo, Hiroshi Kuroda, Nobuyuki Tanaka, Kazuko Murata, Naoto Ishii, Kazuo Sugamura, STAM, Signal Transducing Adaptor Molecule, Is Associated with Janus Kinases and Involved in Signaling for Cell Growth and c-myc Induction Immunity. ,vol. 6, pp. 449- 457 ,(1997) , 10.1016/S1074-7613(00)80288-5
Justus Duyster, Ren-Yuan Bai, Stephan W Morris, Translocations involving anaplastic lymphoma kinase (ALK) Oncogene. ,vol. 20, pp. 5623- 5637 ,(2001) , 10.1038/SJ.ONC.1204594
A. V. Galkin, J. S. Melnick, S. Kim, T. L. Hood, N. Li, L. Li, G. Xia, R. Steensma, G. Chopiuk, J. Jiang, Y. Wan, P. Ding, Y. Liu, F. Sun, P. G. Schultz, N. S. Gray, M. Warmuth, Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 270- 275 ,(2007) , 10.1073/PNAS.0609412103
Arianna Donella-Deana, Oriano Marin, Luca Cesaro, Rosalind H. Gunby, Anna Ferrarese, Addolorata M. L. Coluccia, Carmen J. Tartari, Luca Mologni, Leonardo Scapozza, Carlo Gambacorti-Passerini, Lorenzo A. Pinna, Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity. Biochemistry. ,vol. 44, pp. 8533- 8542 ,(2005) , 10.1021/BI0472954
Ronald Palacios, Michael Steinmetz, IL3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo Cell. ,vol. 41, pp. 727- 734 ,(1985) , 10.1016/S0092-8674(85)80053-2
Shin-Ichiro Fujiwara, Yoshihiro Yamashita, Young Lim Choi, Hideki Watanabe, Kentaro Kurashina, Manabu Soda, Munehiro Enomoto, Hisashi Hatanaka, Shuji Takada, Keiya Ozawa, Hiroyuki Mano, None, Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening Leukemia & Lymphoma. ,vol. 48, pp. 978- 986 ,(2007) , 10.1080/10428190701225882
Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, Sarada Gurubhagavatula, Ross A. Okimoto, Brian W. Brannigan, Patricia L. Harris, Sara M. Haserlat, Jeffrey G. Supko, Frank G. Haluska, David N. Louis, David C. Christiani, Jeff Settleman, Daniel A. Haber, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib The New England Journal of Medicine. ,vol. 350, pp. 2129- 2139 ,(2004) , 10.1056/NEJMOA040938
Marc Pollmann, Reza Parwaresch, Sabine Adam-Klages, Marie-Luise Kruse, Friedrich Buck, Hans-Juergen Heidebrecht, Human EML4, a novel member of the EMAP family, is essential for microtubule formation Experimental Cell Research. ,vol. 312, pp. 3241- 3251 ,(2006) , 10.1016/J.YEXCR.2006.06.035