Effect of Physical Exercise on Endometriosis Experimentally Induced in Rats

摘要: Endometriosis is characterized by the growth of endometrial tissue outside uterine cavity. The prevalence endometriosis among women experiencing pain, infertility, or both as high 35% to 50%. most common symptoms are dysmenorrhea, dyspareunia, chronic pelvic and infertility. Evidence has suggested that result from a local inflammatory peritoneal reaction caused ectopic implants undergo cyclic bleeding. On other hand, regular physical exercise seems have protective effects against diseases involve processes such type 2 diabetes colon breast cancer. this basis, it possible practice may beneficial on endometriosis. Therefore, objective study was evaluate anti-inflammatory effect experimentally induced in rats. Seventy female Wistar rats were divided into 7groups 10 animals each. Animals performed light (swimming once week), moderate 3 times intense 5 week) before after induction. At end experimental protocol, reduction size endometriotic lesions observed regardless its frequency, with greater groups practicing activity; an increase FAS levels decrease matrix metalloproteinases 9 proliferating cell nuclear antigen (PCNA)levels also observed. immunohistochemistry results did not lead conclusive results. As expected, oxidative stress reduced all groups. These show could be beneficial, at least part, for treatment