[Aluminum--occurrence and toxicity for organisms].

作者: W Ochmański , W Barabasz

DOI:

关键词: EnzymeBiochemistryToxicityPhosphataseNAD+ kinaseHexokinaseCarcinogenTransferrinChemistryCalciumToxicology

摘要: Aluminium (Al.) is an ubiquitous element found in every food product. The sources of Al. are especially corn, yellow cheese, salt, herbs, spices, tea and tap water. In household Al.-made ware a major source the element. may cause diseases humans, hampers many metabolic processes turnover calcium, phosphorus iron. Salts bind to DNA, RNA, inhibit such enzymes as hexokinase, acid alkaline phosphatases, phosphodiesterase phosphooxydase. salts harmful nervous, hematopoietic systems skeleton. gets organism with food, water, cosmetics, from aluminium containers. Toxicity comes substitution Mg Fe ions effecting disturbances intracellular signaling, excretory functions cellular growth. Neurotoxic action probably ATP, what finally influences function ATP using-enzymes. There observations experimental models proving responsible for Alzheimer disease development. skeletal system results diminished resistance thus tendencies breaking, lower collagen synthesis slowing down mineralisation. Low erythropoietin production, inhibition hem-synthesing binding transferrin, effects anaemia. Carcinogenic were nor proved denied, but high concentrations neoplastic cells. conclusion, we should introduce prophylactic measures less intake esp. avoiding use nad controlling content.

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