Complexation between oleanolic and maslinic acids with native and modified cyclodextrins

摘要: Oleanolic (OA) and maslinic (MA) acids are two natural triterpenoids with a wide range of beneficial effects for human health. However, their low solubility permeability make application in the food, or pharmaceutical, industry difficult. The complexation OA MA α- β-, γ-, HP-α-, HP-β- HP-γ-CDs, under different pH temperature conditions, has been studied. Neither nor HP-α-CDs formed inclusion complexes, while HP-γ-CDs provided AL type γ-CDs BS phase diagrams. Complexation was shown to be more stable case but efficiency greater OA. Increasing media tended improve process triterpenic acids.