Characterization of carvacrol beta-cyclodextrin inclusion complexes as delivery systems for antibacterial and antioxidant applications

作者: Laura E. Hill , Carmen L. Gomes , Emerson H. Santos , Juliane A. Kamimura

DOI: 10.1016/J.LWT.2014.08.046

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摘要: Abstract Carvacrol is a good natural antimicrobial and antioxidant agent; however, its poor aqueous solubility high volatility limit application in food systems. Beta-cyclodextrin (ΒCD) able to encapsulate hydrophobic molecules improving reducing volatility. ΒCD-carvacrol inclusion complexes were prepared using kneading (KN) freeze drying (FD) methods. Sizes of 441 ± 12 nm 899 ± 44 nm entrapment efficiencies 83.79 ± 2.89% 91.31 ± 0.41% for KN FD BCD-carvacrol complexes, respectively. Polydispersity index was higher (P

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