Evaluation of the thyroid nodule.

作者: Christopher D. Lansford , Theodoros N. Teknos

DOI: 10.1177/107327480601300202

关键词: Nodule (medicine)MedicineRadiologyThyroidCarcinomaUltrasonographyThyroid nodulesGeneral algorithmPhysical examinationAspiration biopsy

摘要: Background: Thyroid nodules are common, yet treatment modalities range from observation to surgical resection. Because thyroid frequently found incidentally during routine physical examination or imaging performed for another reason, physicians a diverse of specialties encounter nodules. Clinical decision making depends on proper evaluation the nodule. Methods: The current literature was reviewed and synthesized. Results: Current evidence allows formulation recommendations general algorithm evaluating incidental Conclusions: Only small percentage require management. Diagnosis selection risk stratification by history, examination, ancillary tests. Nodules causing airway compression those at high carcinoma should prompt treatment. In larger than 1 cm, fine-needle aspiration biopsy is central as it accurate, low risk, cost effective. Subcentimeter nodules, often obtained purpose, can usually be evaluated ultrasonography. Other laboratory evaluations have specific more limited roles. An nodule presented.

参考文章(69)
H. Jarosz, A. Mccall, E. Paloyan, A. M. Lawrence, The incidence of thyroid carcinoma in solitary cold nodules and in multinodular goiters. Surgery. ,vol. 100, pp. 1128- 1132 ,(1986)
Bartolome Burguera, Hossein Gharib, Thyroid incidentalomas. Prevalence, diagnosis, significance, and management. Endocrinology and Metabolism Clinics of North America. ,vol. 29, pp. 187- 203 ,(2000) , 10.1016/S0889-8529(05)70123-7
Paul E. Wakely, Patricia A. Thomas, Jan F. Silverman, Tarik M. Elsheikh, Stephen S. Raab, Pediatric Thyroid Nodules: Disease Demographics and Clinical Management as Determined by Fine Needle Aspiration Biopsy Pediatrics. ,vol. 95, pp. 46- 49 ,(1995)
Bertil Hamberger, Hossein Gharib, L. Joseph Melton, John R. Goellner, Alan R. Zinsmeister, Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care. The American Journal of Medicine. ,vol. 73, pp. 381- 384 ,(1982) , 10.1016/0002-9343(82)90731-8
Nina L. Shapiro, Neil Bhattacharyya, Population-based outcomes for pediatric thyroid carcinoma. Laryngoscope. ,vol. 115, pp. 337- 340 ,(2005) , 10.1097/01.MLG.0000154743.71184.09
Christopher R. McHenry, Sandra J. Slusarczyk, Amer Khiyami, Recommendations for management of cystic thyroid disease. Surgery. ,vol. 126, pp. 1167- 1172 ,(1999) , 10.1067/MSY.2099.101423
Michael W. Ashcraft, Andre J. Van Herle, Management of thyroid nodules. II: Scanning techniques, thyroid suppressive therapy, and fine needle aspiration Head & Neck Surgery. ,vol. 3, pp. 297- 322 ,(1981) , 10.1002/HED.2890030406
Andreas Machens, Oliver Gimm, Raoul Hinze, Wolfgang Höppner, Bernhard O. Boehm, Henning Dralle, Genotype-phenotype correlations in hereditary medullary thyroid carcinoma: oncological features and biochemical properties. The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 1104- 1109 ,(2001) , 10.1210/JCEM.86.3.7290
Betül A. Hatipoglu, Theresa Gierlowski, Eileen Shore-Freedman, Wendy Recant, Arthur B. Schneider, Fine-needle aspiration of thyroid nodules in radiation-exposed patients. Thyroid. ,vol. 10, pp. 63- 69 ,(2000) , 10.1089/THY.2000.10.63
A. MACHENS, J. UKKAT, M. BRAUCKHOFF, O. GIMM, H. DRALLE, Advances in the management of hereditary medullary thyroid cancer. Journal of Internal Medicine. ,vol. 257, pp. 50- 59 ,(2005) , 10.1111/J.1365-2796.2004.01423.X