Longitudinal Study of Weight, Appetite, Performance Status, and Inflammation in Advanced Gastrointestinal Cancer

作者: Patricia O'Gorman , Donald C. McMillan , Colin S. McArdle

DOI: 10.1207/S15327914NC352_5

关键词: Performance statusLongitudinal studyAppetiteEndocrinologyLost WeightGastroenterologyWeight lossInflammationGastrointestinal cancerInternal medicineMedicineAlbumin

摘要: There is increasing evidence that, in most patients with advanced cancer, weight loss associated an inflammatory response. To examine the temporal relationship between loss, appetite, performance status, and response, 50 gastrointestinal cancer were observed for six weeks. Patients grouped according to whether they had lost ( = 3%, n 16), stable 3% change, 25), or gained 9). At baseline, group that subsequently lower albumin higher C-reactive protein concentrations (p 0.05). On follow-up, there was increase concentration reductions triceps skinfold thickness Karnofsky status weight-losing In contrast, improved Over eight weeks, a difference changes of =...

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