The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists.
作者： Huayun Deng , Ye Fang
DOI: 10.3390/PH6040500
关键词: Fenoldopam 、 GPR35 、 Redistribution (chemistry) 、 Benserazide 、 Catechol 、 Pyrogallol 、 Medicine 、 Pharmacology
摘要: Nearly 1% of all clinically used drugs are catecholics, a family catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin fenoldopam, display agonistic activity against GPR35.
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