THE EFFECTS ON PULMONARY ARTERY PRESSURE OF EARLY SURGICAL REPAIR OF VENTRICULAR SEPTAL DEFECT IN SMALL CHILDREN

摘要: Objective: Significant changes have occurred in the management of pediatric patients with ventricular septal defect such as early surgical repair de- fects. The objective this study was to investigate effects closure isolated defects on pulmonary artery pressure. Materials and Methods: Forty-nine undergoing surgery due vent- ricular between January 2001 2004 were enrolled study. classified into two groups terms their age at time operation. Those who had been operated before 2 formed Group 1 (n=24) those after (n=25). Preoperative postoperative (at year) echo- cardiographic measurements pressure values recor- ded for all patients. Results: No statistically significant differences found preoperative or vascu- lar resistance values. However, mean significantly lower (24.41 ± 0.63 mmHg) when compa- red (37.06 1.53 (p = 0.0001). late mortality during a follow-up period years. Conclusion: Our results suggest that is more beneficial an earlier onset vascular disease. Surgery age, if possible infancy, may offer opportunity lead nearly normal life VSD. Key Words: Ventricular Septal Defect, Pulmonary Hypertension, Surgical Re- pair.. KUCUK COCUKLARDA VENTRIKULER SEPTAL DEFEKTIN ER- KEN CERRAHI ONARIMININ PULMONER ARTER BASINCI UZE- RINDEKI ETKILERI OZ Amac: Ventrikuler defektli pediatrik hastalarin tedavisinde, defektlerin erken cerrahi onarimi gibi onemli degisiklikler olmustur. Bu calismanin amaci, izole ventrikuler kapatilmasinin pulmoner arter basinci uzerindeki etkilerinin arastirilmasidir. Gerec ve Yontem: Ocak - arasinda fect nedeniyle tedavi uygulanan 49 hasta calismaya dahil edildi. Hata- ameliyattaki yaslarina gore iki gruba ayrildi. Iki yasindan once opera edi- len hastalar Grup (n=24), sonar opere edilenler 2’yi (n=25) olusturdu. Preoperatif postoperatif (1.yil) ekokardiyografik degerleri tum icin kaydedildi. Bulgular: vaskuler rezistans acisindan grup istatistiksel olarak anlamli bir fark bu- lunmadi. Buna karsin, ortalama basinc degerleri- nin 1’de (24,41 0,63 mm-Hg) (37,06 1,53mm-Hg) ile karsilas- tirildiginda belirgin dusuk oldugu gozlendi Gruplarda orta- lama yillik izlem suresince veya gec mortalite olusmadi. Sonuc: Sonuclarimiz operasyonun yasta , hastalik baslangicindan daha yararli oldugunu gostermektedir. Erken yasta, mum- kunse infant doneminde VSD’li normale yakin yasam surme sansi saglayabilmektedir. Anahtar Kelimeler: Defekt, Pulmoner Hipertansiyon, Cer- rahi Onarim.